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Trials and Studies

Here are the current research studies being conducted at Gateshead Health NHS Foundation Trust.

Contact details are listed if you are interested in taking part in any of the studies. If you don’t feel that any of these studies are suitable, please register on the Making Research Better website to receive information about future studies.

Diabetes

ADDRESS2 (Dr Jola Weaver) 

ADDRESS2 is a database for children (aged 5 and over) and adults who have been newly diagnosed (in the past 6 months) with Type 1 Diabetes.

Register your details if you would like to hear about opportunities to take part in clinical research.

Please contact Wendy Stoker (Research Nurse) for more information - Tel: 0191 445 8038

 

TRIAL NET (Dr Vasileios Tsatlidis)

TRIAL NET - the aim of this genetic study is to learn how Type 1 diabetes occurs.  It is open to close relatives of people with Type 1 Diabetes who are most at risk of developing the disease.

Please contact Wendy Stoker (Research Nurse) for more information - Tel: 0191 445 8038

 

Cancer

ADD - ASPIRIN (Dr Nicola Cresti)

We are testing whether taking aspirin regularly after treatment for early stage cancer stops or delays the cancer coming back.

We are testing different doses of aspirin. Some people will receive a dummy drug (placebo).

Please contact David Norman (Research Nurse) for more information - Tel: 0191 445 3224

 

Gastroenterology

Contact Me  (Dr Dina Mansour/ Dr Jamie Barbour)

How effective is Consent for Contact in increasing opportunities to participate, and patient recruitment to IBS clinical trials?

To find out more please contact Ann Wilson on (0191) 445 6283 or Maureen Armstrong on (0191) 445 8414. 

 

IBD Bioresource  (Dr Dina Mansour/ Dr Jamie Barbour)

The IBD BioResource aims to help research into the causes of Crohn’s and colitis.

The IBD BioResource aims to support studies looking at how genes and environmental factors influence disease and response to therapy. By gaining more information on the genes involved in Crohn’s disease and ulcerative colitis and by understanding the differences in their function and integrating information regarding environmental influences including the microbiota we hope to gain insights regarding causal mechanisms, potential new therapies and treatment approaches for IBD to reduce the burden of disease, and begin to think about a cure.

To find out more please contact Ann Wilson on (0191) 445 6283 or Maureen Armstrong on (0191) 445 8414. 

 

PREdiCCt (Dr Dina Mansour/ Dr Jamie Barbour)

The main goal of the PREdiCCt study is to better understand the factors that trigger or increase the risk of a flare of Crohn’s disease or ulcerative colitis

In recent years we’ve got better at understanding the genetic risk factors and some of the disturbances in the immune system that lead to IBD. However, we are still far away from knowing just what triggers a flare nor can we predict what course the illness will follow in any given individual. The aim of the PREdiCCt study is to help us understand how factors in the environment, including diet and the bugs that live in the gut, increase or reduce the risk of a flare in Crohn’s and colitis.

To find out more please contact Ann Wilson on (0191) 445 6283 or Maureen Armstrong on (0191) 445 8414.

 

 UKPBC (Dr Dina Mansour)

Adults with a diagnosis of Primary biliary cholangitis (PBC) 

Identification of genetic variants associated with important PBC sub-groups, including the following: PBC patients with rapidly progressive disease; those with severe pruritus; those with severe fatigue; PBC patients with a family history of PBC, and those with additional autoimmune conditions.

To find out more please contact Ann Wilson on (0191) 445 6283 or Maureen Armstrong on (0191) 445 8414


Cipher (Dr Paul O’Loughlin)

UK Cohort study to Investigate the prevention of Parastomal Hernia. Around 20,000 people each year have an operation to form a stoma. This is a procedure to divert faeces away from the gastro-intestinal tract (bowel) and is usually required if the bowel becomes damaged either by injury or disease. Most patients who have this operation have a good recovery and are able to manage their stoma well. However, a small number of patients develop a complication called a parastomal hernia (PSH). This is a bulge that develops under or near the stoma, which is caused by weakening of the muscles in the tummy. Unfortunately, we do not know why some patients develop a parastomal hernia and others do not but we think it may be related to how the stoma is formed. Our research aims to find out which surgical factors are linked with parastomal hernias.

 To find out more please contact Ann Wilson on (0191) 445 6283 or Maureen Armstrong on (0191) 445 8414.

 

PQIP (Dr Andrew Bracewell)

PQIP – A trial looking at what happens at our hospital before, during and after patients have major surgery on their bowel to see if improvements can be made.

Please contact Amanda Mulholland or Jenny Ritzema (Research Nurse) for more information - Tel: 0191 445 6481

 

 Hepatology

UKAIH (Dr Dina Mansour)

UK-AIH is a study for adults with autoimmune hepatitis in the UK. It will collect information from any patient who wishes to participate. Some people will be asked to donate blood samples, answer questionnaires, and let researchers use any liver tissue samples that are taken as part of their normal medical care. All this information will be studied to identify new tests and treatments

To find out more please contact Ann Wilson on (0191) 445 6283 or Maureen Armstrong on (0191) 445 8414.

 

Dementia and Neurodegeneration

Skin Metabolites in Parkinson's Disease (Dr Richard Athey)

This trial involves a skin swab being taken to see if it can help diagnose Parkinson’s disease earlier.

Please contact Bryony Storey (Research Nurse) for more information - Tel: 0191 445 6317

 

 SYMBAD (Professor Alan Thomas)

 A drug trial for people who have Alzheimer's Disease or Alzheimer's and Vascular Dementia (combined) who experience agitation.

Please contact Elaine Siddle (Research Nurse)or Bryony Storey (Research Nurse) for more information - Tel: 0191 445 6317

 

 

 

 

 

 

 

 

 

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